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The Viagra (sildenafil) treatment of male erectile dysfunction
will be a pharmaceutical event for the history books. This is a
drug that effectively treats a male's inability to achieve or
maintain an erection sufficient for satisfactory sexual
performance. Is it a widespread problem? It is estimated that 39%
of men 40 years of age and 67% of men 70 years of age have this
problem.
A recent collaborative study looked at the efficacy of this
treatment--Goldstein I et al.: Oral sildenafil in the
treatment of erectile dysfunction. N Engl J Med 1998;338:1397-
1404. Various dose regimens were used, but overall in men,
it improved erectile function (equivalent to the arousal phase in
women with clitoral swelling and vascular swelling) by almost
100%. It improved orgasmic function by about 20% and it had
ZERO effect on sexual desire. The overall intercourse
satisfaction increased by 100%. The major side effects increased
as dose increased and were predominantly headache, flushing (both
about 20-30%) and stomach upset (about 10%). Interestingly the
side effects were only a small proportion of the reasons for
discontinuing the study (7-15%, at different doses, stopped
participating in the study).
Why should we write about this at Woman's Diagnostic Cyber?
Because there will be a significant impact on women whose
partners use Viagra. There will be more frequent demands for
sexual intercourse which may or may not be welcome. Many women
who are menopausal report a decreased sexual desire even if they
are on estrogen replacement therapy. If women are having any
vaginal dryness, they may fear pain with sexual relations and
that certainly turns off libido. Even if women are on estrogen
replacment and have good vaginal lubrication, if they are having
vaginal intercourse less frequently than once per two weeks, they
will have loss of vaginal elasticity that can cause discomfort or
pain when they first start to increase the frequency of sexual
relations.
Sexual desire is a very complex subject-- see previous news:
There are many different components to possible sexual desire
barriers.
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Fear of pain or discomfort with sexual intercourse
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Lack of, or numbness to, arousal by normal physical sexual stimuli
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Lack of, or numbness to, arousal by normal visual or verbal sexual stimuli
Aversion to intimacy with one's partner due to:
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Hygiene problems
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Lovemaking skills
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Anger at one's partner for current or past behavior
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Medications that lessen sexual desire
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Physical disabilities or pain affecting lovemaking
The list could probably go on and on with different problems that
will demand different solutions or treatments. I predict that
this Viagra epidemic will cause epidemics in women:
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asking for Viagra to improve their sexual arousal
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seeking treatment for vaginal dryness, pain and bleeding related
to more frequent sexual intercourse
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seeking androgen (male hormone) therapy to improve sexual desire
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with more major, stressful reactions involving their long-standing
partners
On the up side, there will be many more relationships in which
the intimacy happiness level goes up. That is good!
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