Is all dysplasia HPV related?
I got the results of my cervical biopsy, and my doctor said it was a low grade squamous intraepithelial lesion (LGSIL). He said we weren't going to worry about it, and every three months, he would repeat the pap until it was clear, and if it wasn't clear in 12 months, then he would "LEEP" it back to clear.
I asked him where this came from and he said probably HPV (human papilloma virus), but the lab doesn't check for that so he doesn't know for sure, but in his opinion, all dysplasia is sexually transmitted, i.e., if your pap comes back with LGSIL, then you have HPV, regardless of what the report says. I asked him if he would ask the lab to DNA type for HPV, but he said they don't feel that tells them anything.
My husband and I have only been with each other, ever, and I have always had clear paps. I have read up on this, and I can't seem to find any other reasons for this to have developed so suddenly, after so many clear paps. Are there other possibilities?
Yes. Not all LGSIL or dysplasia comes from HPV. For example we see some related to menopause when estrogens are low. The pathologist is only looking at the nucleus of the cell in relation to the entire cell size.
When the nucleus enlarges, it can be due to any infection or repair work on cervical cells. Any irritation can cause this.
That's why we usually wait for it to clear up on its own. It usually does and you probably won't need a LEEP. HPV is associated with much of abnormal Paps but not all by any means.
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