Women's Health Newsletters 2/13/00 - 3/27/00
***** Woman's Diagnostic Cyber Newsletter ***** February 13, 2000 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ This week from Woman's Diagnostic Cyber ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 1. Cardiac catheterization for diagnosis and therapy 2. Breast pain - different types 3. Reader submitted Q&A - Vaginal opening looseness 4. Breast cancer risk calculator 5. Dealing with cancer chemotherapy effects 6. Humor is healthy Spread the word! Send a copy of this newsletter to someone you know. Note: Some of the long URLs may not wrap as a hyperlink and you may need to cut and paste. ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 1. Cardiac catheterization for diagnosis and therapy ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ Hopefully you will never have to have a procedure as complicated and risky as a cardiac catheterization, but when you do, a thorough understanding can alleviate some anxiety. A site called yoursurgery.com has very good explanations of different procedures such as cardiac catheterization. They explain the anatomy, diseases associated with needing the procedure, historical symptoms and physical findings in patients having to have this procedure, and an explanation of the procedure itself often with multimedia clips of video. Other procedures in addition to cardiac catheterization include: craniotomy shunt for hydrocephalus cataract removal LASIK for vision correction spinal disk removal carotid endarterectomy coronary artery bypass mastectomy chest surgery esophagus surgery hernia repair colon removal gall bladder removal Cesarean section aorta aneurysm surgery prostate surgery hysterectomy hip replacement spinal fusion arthroscopy knee replacement carpal tunnel release ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 2. Breast pain - different types ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ Breast pain comes in different types, cyclical, non cyclical and non breast origin. Cyclical varies with the menstrual cycle and is thought to be hormonal in origin. The pain goes away at sometimes during the menstrual cycle. Progesterone cream or pills may slightly reduce this cyclical pain somewhat. Noncyclical pain is less common than cyclical and tends to occur in a specific area in the breast. It is more common in the 40-50 year age range and is often very difficult to diagnose an exact cause. Sometimes the pain can last for years. While a possible cancer must be ruled out, it is unusual for cancer to present initially with pain. Chest pain can also present as breast pain. Inflammation of where the ribs join the breast bone (costrochondritis) is a common cause. Suspensory ligament pain from poor bra support is another cause. Types of breast pain ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 3. Reader submitted Q&A - Vaginal opening looseness ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ "My doctor has told me that I need to have vaginal reconstruction due to the problems childbirth caused me. He is not pushy about it but says it is my decision whether it would be worth it to have the surgery. My problems are urinary incontinence, vaginal dryness because I am "wide open", and intercourse is not as pleasurable because of my muscles being so weak and loose. I don't know if this is recommended or is my problems just something I have to live with since they are not a medical necessity? " Looseness of the vaginal opening after childbirth can be quite distressing. It can allow increased amounts of air into the vagina during intercourse resulting in both dryness and sometimes noise of the air during sexual relations. Decreased pleasure due to loss of sensation and tightness also occurs. More women will have vaginal opening looseness after childbirth if no episiotomy is performed but healing over time often returns the opening to a tighter state so that intercourse pleasure is not an issue. In some women, however, the looseness persists and then what to do for that becomes an issue. See the discussion at: Vaginal opening looseness ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 4. Breast cancer risk calculator ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ Dr. Steven B. Halls, a radiologist, has created a breast cancer risk calculator. There have been several other such risk estimators available but they all seem to request data a woman is unlikely to know precisely. This calculator is more robust and accepts unknown as data elements. It also gives some helpful explanations of items like mammographic density and how some formulas tend to include carcinoma in situ (not an invasive cancer) and may underestimate risks. There is a good explanation of how the formulas work. I like the way the calculator gives you not only the lifetime risk (up to age 90), but also a woman's risk of breast cancer over the next 5, 10, 20 and 30 years. You can also test out some other risk factors that are not usually included in the formulas but which have been shown to affect risk. Breast risk calculator ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 5. Dealing with cancer chemotherapy effects ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ If you have ever known anyone who has had to have chemotherapy for treatment of a cancer, you know what a double whammy the treatment is on top of a fatiguing disease. What can be done to make the treatment not worse than the disease? At cancerlynx.com there is an excellent brochure with helpful tips of how to deal with the effects of cancer chemotherapy. For fighting the fatigue of the treatment and disease and to conserve all one's energy, an example of the suggestions includes: Bathing Wash hair in shower, not while leaning over sink. Sit to dry off. Use a terry robe instead of drying off with a towel. Use a shower bench or lawn chair to sit while showering. Grooming Sit. Don't lean forward unsupported Rest elbows on counter or dressing table. Use long-handled combs or brushes to avoid holding arms overhead. Dressing Loose-fitting clothing allows easier breathing. Organize early to avoid rushing to dress. Lay out clothes before starting to avoid extra steps. Shopping Make a list first. Organize list by store aisle. Combine errands to reduce the number of trips. Use the grocery cart for support. ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 6. Humor is healthy ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ Feel the need to exercise? Read this from "Ten Foot Stop", a dive medicine newsletter. 1) My grandmother started walking five miles a day when she was 60. She's 97 now & we don't know where in the world she is. 2) The only reason I would take up jogging is so that I could hear heavy breathing again. 3) I joined a health club last year, spent about 400 bucks. Haven't lost a pound. Apparently you have to show up. 4) I have to exercise in the morning before my brain figures out what I'm doing. 5) I don't exercise at all. If God meant us to touch our toes, he would have put them further up our body. 6) I like long walks, especially when they are taken by people who annoy me. 7) I have flabby thighs, but fortunately my stomach covers them. 8) The advantage of exercising every day is that you die healthier. 9) If you are going to try cross-country skiing, start with a small country. 10) I don't jog. It makes the ice jump right out of my glass. ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ That's it for this time. Your BACKUPMD on the Net. Rick Frederick R. Jelovsek MD ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
***** Woman's Diagnostic Cyber Newsletter ***** February 20, 2000 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ This week from Woman's Diagnostic Cyber ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 1. Nickel contact dermatitis - earrings, rings 2. Gastritis and other GI problems 3. Reader submitted Q&A - Perineal body odor 4. Hormone replacement synopsis 5. Grieving a loss 6. Humor is healthy Spread the word! Send a copy of this newsletter to someone you know. ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 1. Nickel contact dermatitis - earrings, rings ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ While less expensive jewelry often has high percentage of nickel, even expensive jewelry has some nickel in it and after years of wear can cause redness and itching on your finger or earlobes. A contact dermatitis like this can be treated with hydrocortisone cream but the challenge is diagnosing that it is indeed a contact allergic reaction. There can also be cross reactions of a skin contact dermatitis to objects that do not contain nickel but that have similar allergens such as: Coins Pool table felt green dye Machine oils used to cut or grind Some eye cosmetics Chromium and cobalt ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 2. Gastritis and other GI problems ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ Anytime someone complains of an upset stomach it gets labelled as a "gastritis". But that diagnosis which refers to an inflammatory condition of the stomach lining can only be made by looking inside the stomach (gastroscopy) or biopsy of the stomach lining. Sometimes a chronic gastritis may be be associated with an increased risk of stomach cancer. Symptoms of gastritis include: nausea, vomitting, pain or discomfort in the upper abdomen, loss of appetite and sometimes vomitting of blood. It is most often caused by ingesting something that is toxic to the stomach lining like alcohol, aspirin, other non steroidal anti-inflammatory drugs, or even bile. It can also be caused by radiation, infection with h. pylori bacteria, and other allergic, vascular or infectious conditions. Gastritis at Gastro.net Gastro Net, an Australian site also has excellent sections on diets and nutrition in various gastrointestinal conditions such as: What is a health diet? Boosting the fibre in your diet Weight reduction diet Diest for irritable bowel syndrome Gastro-oesophageal reflux diet Lactose free diet Gluten free diet for coeliac disease Diet issues in inflammatory bowel disease Gastrointestinal diets ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 3. Reader submitted Q&A - Perineal body odor ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ "My question is do you have any suggestions for how women can maintain a "nice flora scent" throughout the day without using douches frequently? Sometimes usually by lunch time 12:00 noon, when I go to use the restroom I notice a mild to moderate urine smell. I do not currently suffer from a yeast infection, and take acidophillus on a regular basis to maintain a healthy urinary tract and decrease the frequency of yeast infections. I also use a mild soap without dyes or fragrance such as Dove in my genital area to keep it clean and free from irritation." Perineal odor can be due to sweating, urine and vaginal secretions and the interplay of food you ingest whose oils are secreted in sweat and the action of bacteria on these secreted compounds. I have no answer for producing a "nice flora scent" short of using some type of deodorant coverup. But that approach can have its problems too. Perineal odor ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 4. Hormone replacement synopsis ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ For a good review of the current therapeutic regimens for hormone replacement therapy during menopause, you may want to look at this article from the Australian Family Physician online journal. It covers not only the usual immediate symptoms that are relieved and other longer term benefits, but it also discusses different regimens, cyclic (with regular withdrawal bleeding), continuous and low dose oral contraceptives versus different prescription estrogens and progestins. It also discusses which regimens might be used in the different time periods such as right before menopause, immediate post menopause, postmenopause 2-3 years or more, as well as other indications such as: osteopenia/osteoporosis (bone thinning) urogenital atrophy (vaginal dryness, urethral irritation cardiovascular protection after hysterectomy HRT side effects and progestin side effects ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 5. Grieving a loss ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ Losing a loved one or having a stillborn baby or miscarriage are situations that can lead to grief reactions in your friends. How do you recognize these and what can you do about them? Dr. Kirsti A. Dyer has a web site called journeyofhearts.org that is focused on grief reactions. She has some great tips on how to help friends in grief. Avoid chatting, just listen. Your friend's silence is ok. Keep in touch. Help out with the daily routine things. Know the signs and symptoms of depression. ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 6. Humor is healthy ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ Memory and Menopause Three ladies, recently menopausal, were were discussing the merits of estrogen and the travails of short term memory difficulty. One said, "Sometimes I catch myself with a jar of mayonnaise in my hand in front of the refrigerator and can't remember whether I need to put it away, or start making a sandwich." The second lady chimed in, "Yes, some times I find myself on the landing of the stairs and can't remember whether I was on my way up or on my way down." The third one responded, "Well, I'm on estrogen and I'm glad I don't have a memory problem; knock on wood," as she rapped her knuckles on the table, then told them "That must be the door, I'll get it!" ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ That's it for this time. Your BACKUPMD on the Net. Rick Frederick R. Jelovsek MD ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
***** Woman's Diagnostic Cyber Newsletter ***** February 27, 2000 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ This week from Woman's Diagnostic Cyber ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 1. Bacterial vaginosis and preterm labor 2. Estrogens do not slow Alzheimer progression 3. Reader submitted Q&A - Urethral dilatation 4. Sexual dysfunction on antidepressants 5. Education for children with diabetes 6. Health tip to share - Perineal odor 7. Humor is healthy Spread the word! Send a copy of this newsletter to someone you know. Note: Some of the long URLs may not wrap as a hyperlink and you may need to cut and paste. ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 1. Bacterial vaginosis and preterm labor ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ Bacterial vaginosis in pregnancy has been associated with preterm labor. This is a good example of an association which may or not be a cause and effect. If bacterial vaginosis is a cause of preterm labor, then treating it should decrease the incidence of premature birth. This recent New England Journal of Medicine article looked at over 800 women who had ASYMPTOMATIC bacterial vaginosis in pregnancy. They treated half of them with metronidazole (Flagyl(R)) and the other half placebo. They had about a 75% cure rate from the treatment but the incidence of preterm labor was not different in the treated (12.2%) and the placebo (12.5%) groups. Thus it is unlikely that bacterial vaginosis is a cause of preterm labor although it can be a high risk marker for preterm labor. ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 2. Estrogens do not slow Alzheimer progression ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ Estrogen replacement after menopause has been well shown to be associated with a decreased incidence of the new occurrence of Alzheimer disease. What has not been certain is whether there is any role for estrogen to treat women who already have Alzheimer disease. Some evidence suggested that it might, but the study below is a randomized trial of giving women who already have Alzheimer disease estrogen or placebo. The study was reported in the Journal of the American Medical Association (JAMA) in which 120 women with mild or moderate Alzheimer disease were given conjugated estrogens 0.625 mg, 1.25 mg or placebo. Unfortunately the women receiving estrogen progressively worsened over a year at the same rate as those receiving placebo. This study would indicate that estrogens do not slow the progression of Alzheimer disease once a woman has it. Estrogen treatment for Alzheimer progression ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 3. Reader submitted Q&A - Urethral dilatation ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ "My doctor is suggesting that I have urethral dilatations for recurring bladder infections. I am getting conflicting information regarding this procedure. Are they helpful or not?" Most of the time they are not helpful and are not being performed in women by urologists as much as they used to. Some urologists still do them for urethral syndrome and urethral stricture. These conditions and alternatives you might consider are discussed at: Urethral dilatation for chronic UTIs ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 4. Sexual dysfunction on antidepressants ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ Many antidepressants cause sexual dysfunction such as loss of sexual desire, lack of arousal etc. Fluoxetine (Prozac(R)) is notorious for causing loss of sexual desire. One study looked at giving women who were on Prozac and who had reported a deterioration of sexual function one of three therapies: buspirone (Buspar), amantadine, or placebo. After 8 weeks of treatment, all three groups had a significant improvement in sexual function. Yes even the placebo group had the same improvement. This study suggests that there is a significant placebo effect in the study of this problem and any further trials have to be shown to be superior to placebo. Perhaps the major determinant in deterioration of sexual function on antidepressants is the expectation of such a deterioration and any attention that gives hope for improvement will actually give improvement. The bottom line is to be very wary of studies having to do with sexual dysfunction because there are so many different influences on this problem that any given study may not account for. Sexual dysfunction on anti-depressants ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 5. Education for children with diabetes ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ A child with insulin dependent diabetes will have trouble understanding why they need to give themselves an injection. If they are not educated as to why they must take control of their disease, there will be bouts of hyperglycemia and hypoglycemia and episodes of hospitalization. If your child or a friend's child has diabetes, they are not alone. Over 800,000 Americans have diabetes with 30,000 new cases a year. However, children are very reluctant to let other children know they have a chronic disease. This is best handled by the child being able to explain all about diabetes and how it is not contagious. Check out the site Aequilibrium, a compliance counselling web site by Bayer: Children with insulin dependent diabetes Other topics at Aequilibrium include: Aging and Alzheimers Hypertension in African Americans Hemophilia ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 6. Health tip to share ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ To control perineal odor, use baby wipes. Carry a few in a plastic bag when going to work. LUV's extra thick are good for bad days; wipes are also good when you have to go to the hospital. I tell patients to bring them. Our thanks for this tip to: Rose Rubio If you have discovered ways of coping with a disease or condition and it works for you, please share it with us: Health tip suggestion form ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 7. Humor is healthy ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ The room was full of pregnant women and their partners, and the Lamaze class was in full swing. The instructor was teaching the women how to breathe properly, along with informing the men how to give the necessary assurances at this stage of the plan. The teacher then announced, "Ladies, exercise is good for you. Walking is especially beneficial. And, gentlemen, it wouldn't hurt you to take the time to go walking with your partner!" The room really got quiet. Finally, a man in the middle of the group raised his hand. "Yes?" replied the teacher. "Is it all right if she carries a golf bag while we walk?" ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ That's it for this time. Your BACKUPMD on the Net. Rick Frederick R. Jelovsek MD ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
***** Woman's Diagnostic Cyber Newsletter ***** March 5, 2000 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ This week from Woman's Diagnostic Cyber ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 1. How common are thyroid abnormalities? 2. A guide for cancer survivors 3. Reader submitted Q&A - Cyclic pelvic pain 4. Diet meds (orlistat) and long term obesity 5. Progesterone cream not effective on endometrium 6. Health tip to share - Cold sore treatment 7. Humor is healthy Spread the word! Send a copy of this newsletter to someone you know. Note: Some of the long URLs may not wrap as a hyperlink and you may need to cut and paste. ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 1. How common are thyroid abnormalities? ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ Thyroid disease may be more common than we think. This study in Colorado, USA screened over 25000 individuals at a State Health Fair using blood measurements of TSH (thyroid stimulating hormone). They found that 9.5% of the population had laboratory values consistent with hypothyroidism and 2.2% had values indicating hyperthyroidism. This may be an overestimate of thyroid disease in the population because the fair participants were volunteers and may have self-selected, however it is still a high incidence. It reminds us to be sure to liberally test for thyroid abnormalities if there are any suggestive symptoms. In women, menstrual abnormalities are common with hypothyroidism. Prevalence of abnormal thyroid function ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 2. A guide for cancer survivors ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ Survivors of cancer treatment have both physical and emotional concerns. While there are differences in concerns about pain, physical problems and sexuality depending upon the specific type of cancer a woman has, there are also many common concerns that survivors of all different types of cancer have. Finishing the main cancer treatment can be more frightening than full of the relief you think would occur. Leaving the medical support team and being on your own is anxiety provoking. And what about taking care of your general health in the areas other than the cancer area? You cannot forget those other health habits and checkups. Perhaps returning to work and the way other coworkers view a survivors ability is a major concern requiring adjustment. Up to 25% of cancer survivors returning to their place of employment face significant bias both from employers and coworkers. Even if you have never had cancer, reading this Cancer Survivor's Guide from the National Institutes of Health National Cancer Institute can help you understand what others go through with a cancer diagnosis and treatment. Facing forward ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 3. Reader submitted Q&A - Cyclic pelvic pain ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ "I have lower right abdominal pain 3 days each month, 7-10 days before my period. I have had an internal ultrasound which was negative. Any ideas what might be causing this? Also the pain mostly happens at around 1:30-2:30 in the a.m." We can sometimes get a hint of what causes pelvic pain depending upon when in the menstrual cycle the pain occurs and for how long. At 7-10 days before menses we think of the corpus luteum which is enlarging on an ovary. At time of menses, pain makes us think of blockage to menstrual outflow as well as endometriosis and adenomyosis. There can also be other causes and atypical pain presentations so you may want to look at our article at: Cyclic abdominal and pelvic pain ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 4. Diet meds (orlistat) and long term obesity ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ A recently introduced drug called orlistat (trade name Xenical(R)) is being used as an adjunct to diet by many weight loss centers and diet programs. This drug blocks or inhibits gastrointestinal (GI) enzymes called lipases. These are involved in the absorption of triglycerides, a form of fat in food, from the GI tract. Orlistat is minimally absorbed but has a tendency to cause loose bowel movements because the fat just passes through rather than being absorbed. This study looked at use of orlistat by primary care physicians over a one year period along with diet. Two doses, 60 mg and 120 mg three times a day were compared with placebo. Over the year, obese patients taking orlistat 60 mg and 120 mg lost 7 and 8 kg (15.4 and 17.6 pounds) compared with 4.1 kg (9 lbs) for those taking placebo. At the end of two years, 24% of those taking placebo maintained a 5% weight loss compared with about 34% of the orlistat groups. Thus this seems to be an effective weight loss medication when combined with diet. Use of orlistat for weight loss ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 5. Progesterone cream not effective on endometrium ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ Many women are using micronized progesterone cream as part of their hormonal replacement therapy. Among other reasons for this is the fact that oral progestins, and even oral micronized progesterone, results in more adverse mood side effects. The cream tends not to cause those adverse effects. One of the questions that has not been answered is whether the progesterone absorbed through the skin is enough to block the effect of estrogen on the endometrium so a woman with a uterus is not at risk for endometrial cancer. The study below looked at 3 different doses of the progesterone skin cream using a daily dose of 16 mg, 32 mg, or 64 mg, and none of them produced high enough blood levels or endometrial levels to change the endometrial response. This means that women who are on estrogens and still have a uterus cannot use the progesterone cream to totally replace the oral progesterone pills which protect a woman from developing endometrial cancer. Progesterone cream's effect on endometrium ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 6. Health tip to share - Cold sore treatment ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ For a cold sore of the mouth, get one of the styptic pencils from the drug store. The ones used if you cut yourself shaving. Touch the pencil to the sore. It burns and then tastes salty but it really numbs the cold sore and it is no longer painful. Anonymous If you have discovered ways of coping with a disease or condition and it works for you, please share it with us: Health tip suggestion form ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 7. Humor is healthy ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ Heaven Life An 85 year old couple, having been married almost 60 years, died in a car crash. They had been in good health the last ten years mainly due to the wife's interest in health food, and exercise. When they reached the pearly gates, St. Peter took them to their mansion which was decked out with a beautiful kitchen and master bath suite and Jacuzzi. As they "oohed and aahed" the old man asked Peter how much all this was going to cost. "It's free," Peter replied, "this is Heaven." Next they went out back to survey the championship golf course that the home backed up to. They would have golfing privileges everyday and each week the course changed to a new one representing the great golf courses on earth. The old man asked, "what are the green fees?". Peter's reply, "This is heaven, you play for free." Next they went to the club house and saw the lavish buffet lunch with the cuisines of the world laid out. "How much to eat?" asked the old man. "Don't you understand yet? This is heaven, it is free!" Peter replied with some exasperation. "Well, where are the low fat and low cholesterol tables?" the old man asked timidly. Peter lectured, "That's the best part...you can eat as much as you like of whatever you like and you never get fat and you never get sick. This is Heaven." With that the old man went into a fit of anger, throwing down his hat and stomping on it, and shrieking wildly. Peter and the man's wife both tried to calm him down, asking him what was wrong. The old man looked at his wife and said, "This is all your fault. If it weren't for your blasted bran muffins, I could have been here ten years ago!" ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ That's it for this time. Your BACKUPMD on the Net. Rick Frederick R. Jelovsek MD ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
***** Woman's Diagnostic Cyber Newsletter ***** March 12, 2000 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ This week from Woman's Diagnostic Cyber ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 1. Multiple chemical sensitivity disorder 2. Herb - drug interactions 3. Reader submitted Q&A - Irregular menses 4. Bid for your own elective surgery 5. Breast cancer growth - A tutorial 6. Health tip to share - Lysine to prevent cold sores 7. Humor is healthy Spread the word! Send a copy of this newsletter to someone you know. Note: Some of the long URLs may not wrap as a hyperlink and you may need to cut and paste. In last week's article about progesterone cream not being effective to block estrogen's cancer effect in women with a uterus, please remember that the authors were testing doses that are generally available over-the-counter, not prescription doses. Prescription doses of progesterone cream to apply externally on the skin are much higher (100 - 400 mg per dose) and likely will be protective against endometrial cancer. Scientific studies have not been done to confirm this, so be sure to discuss use of progesterone cream with your doctor. There may still be some risk compared to taking the progesterone orally. ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 1. Multiple chemical sensitivity disorder ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ This syndrome is somewhat like chronic fatigue syndrome or chronic fibromyalgia syndrome in that it is not a well defined entity but one that has multiple symptoms in many different organ symptoms. It often begins as an acute or chronic exposure to a chemical toxicant. Symptoms include difficulty breathing, sleeping and/or concentrating, memory loss, migraines, nausea, abdominal pain, chronic fatigue, aching joints and muscles, and irritated eyes, nose, ears, throat and/or skin. There may also be some overlap or a relationship of multiple chemical sensitivity disorder to Sick Building syndrome and Gulf War syndrome. Treatment is basically just to avoid exposure to chemical triggers. Research is still going on in this area. To see fact sheets and other information resources about this, visit: Multiple chemical sensitivity disorder ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 2. Herb - drug interactions ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ Just as prescription medications can interact and cause adverse health effects, so can health food store herbal preparations and some prescription meds. A common interaction is to potentiate anticoagulant therapy so that something like gingko biloba, ginseng or feverfew can cause or worsen bleeding from aspirin, clopidogrel (Plavix), dipyridamole (Persantine), ticlopodine (Ticlid), or warfarin (Coumadin). Ephedra is used in weight loss and asthma. It can be toxic and cause heart attack, seizure or death when used with certain decongestants or even stimulants such as excessive caffeine. Kava can produce deep sedation and even coma when used with alprazolam (Xanex (R)) and St John's Wort can interact with Zoloft (R). This article at Mayohealth.org is worth reading if you are taking any herbal preparations on a regular basis. Herb-drug medication interactions ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 3. Reader submitted Q&A - Irregular menses ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ "What daily hormone supplement do you recommend to improve an irregular menstrual cycle?" It depends upon what type of menstrual irregularity we are talking about. Also it depends upon whether the goals of treatment are to regulate the cycle for predictability or in an attempt to conceive a pregnancy. There are several different patterns of irregular menses. Sometimes periods vary from 3-6 weeks from the start of one to the start of another but rarely are menses skipped. Two other irregular menses patterns are characterized by skipping periods. In one type estrogens are low because of no egg (follicle) development and in the other type, estrogens tend to be high because of arrested follicle development. Polycystic ovarian syndrome would fall under this category. For a discussion of these types of irregular patterns and what you can do about them with non prescription or prescription treatments, see: Hormonal treatment of irregular menses ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 4. Bid for your own elective surgery ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ It was bound to happen. A California firm has created a reverse auction in which you can bid on what you are willing to pay for any of several elective procedures; ones not covered by most insurance plans such as: Cosmetic Surgery Botox injection Breast Enlargement Breast Lift Breast Reconstruction Breast Reduction More... facelifts, eyelids etc. Podiatric Surgery Bunion Surgery Vision Surgery LASIK Surgery Cosmetic Dentistry Bonding And Veneers Implants Porcelain Crowns Teeth Whitening I suspect that most of the bidders are currently California or West Coast physicians but I do not know since they do not list the locales on the site. Maybe I'll have to just go ahead and make a bid to find out. The procedure to fix a bunion by a podiatrist looked like it had a fair number of requests and bids. Check out Medicineonline.com Bid for elective surgery ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 5. Breast cancer growth - A tutorial ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ It can be difficult to understand why some cancers seem to come on quickly while others are quite slow growing. This tutorial about breast cancer growth helps explain the concept of cell doubling time. It takes about 23 doubling times to go from one cancer cell to become a mass large enough to be seen on mammogram. It takes about 30 doubling times to become large enough to be felt as a lump, about one billion cells. Doubling times may be as short as 10 days or as long as several years. This means that a breast cancer with a cell doubling time of 2 months can show up on xray in 4 years while one with a doubling time of 2 years will show up in 46 years. For more information about other breast cancer risk factors, see the article at Whispers Magazine by Dr. William Wolberg. Breast cancer tutorial ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 6. Health tip to share - Lysine to prevent cold sores ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ Stress, illness, and exposure to the sun will bring out cold sores. My first symptom is a burning or tingling on my lip (it's always the same location). At this first sign, I take 2000 mg of Lysine for 3 days, and it keeps the cold sore from coming out. I've been "cold sore" free for 5 years now, so it must have some affect on the virus cell! This doesn't help once the cold sore erupts. Our thanks to SH for this tip! If you have discovered ways of coping with a disease or condition and it works for you, please share it with us: Health tip suggestion form ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 7. Humor is healthy ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ A woman was out golfing one day when she hit her ball into the woods. She went into the woods to look for it and found a frog in a trap. The frog said to her, "If you release me from this trap, I will grant you 3 wishes." The woman freed the frog and the frog said, "Thank you, but I failed to mention that there was a condition to your wishes-that whatever you wish for, your husband will get 10 times more or better!" The woman said, "That would be okay," and for her first wish, she wanted to be the most beautiful woman in the world. The frog warned her, "You do realize that this wish will also make your husband the most handsome man in the world, an Adonis, that women will flock to." The woman replied, "That will be okay because I will be the most beautiful woman and he will only have eyes for me." So, KAZAM - she's the most beautiful woman in the world! For her second wish, she wanted to be the richest woman in the world. The frog said, "That will make your husband the richest man in the world and he will be ten times richer than you." The woman said, "That will be okay because what is mine is his and what is his is mine." So, KAZAM she's the richest woman in the world! The frog then inquired about her third wish, and she answered, "I'd like a mild heart attack." ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ That's it for this time. Your BACKUPMD on the Net. Rick Frederick R. Jelovsek MD ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
***** Woman's Diagnostic Cyber Newsletter ***** March 19, 2000 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ This week from Woman's Diagnostic Cyber ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 1. Why receding gums are of concern 2. Glucosamine and chondroitin for osteoarthritis 3. Reader submitted Q&A - Hysterectomy and chronic fatigue and fibromyalgia syndromes 4. Silicone implants unrelated to connective diseases 5. Genetically altered food squabble 6. Health tip to share - Pecans and cholesterol 7. Humor is healthy We need some more Health tips to share! Spread the word! Send a copy of this newsletter to someone you know. Note: Some of the long URLs may not wrap as a hyperlink and you may need to cut and paste. ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 1. Why receding gums are of concern ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ As many as 3 out of 4 adults have some form of receding gum disease. This is caused by the plaque build-up under the gums which irritates and eventually destroys the overlying gum. Once the soft gum tissue is gone, big pockets develop between the teeth where more and more bacteria can accumulate. At first the gum tissue left is inflamed and reddened and called "gingivitis". Later this inflammation extends to the bone around the teeth. The bone infection, periodontitis, is the major culprit in causing tooth loss and accounts for 70% of all tooth loss in adults over age 40. Regular brushing and flossing on a daily basis help prevent this as well as periodic professional teeth cleaning. Receding gums A quick quiz from the California Dental Association will tell you if it is likely you may already have some gum disease. Gum disease: a quiz ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 2.Glucosamine and chondroitin for osteoarthritis ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ Glucosamine and chondroitin sulfate have been promoted as home remedies for osteoarthritis. Actually I heard first about this from the veterinarians who were using it to treat arthritis and hip dysplasia in dogs. At the time they were uncertain as to how effective it was and medical physicians still have quite a skepticism about their use in people with osteoarthritis. This review of the literature in the Journal of the American Medical Association (JAMA) looks at human studies to see if it is really helpful. It concluded that there was a moderate to large benefit of these compounds in the literature even though many of the studies were somewhat biased and not of the best quality. These compounds are extracted from animal products and have been shown to be safe during their widespread use in Europe over the last decade. They are absorbed from the stomach and GI tract and help new synthesis of joint cartilage. Doses used in the studies ranged about 800-1200 mg chondroitin sulfate once a day or glucosamine sulfate 1500 mg a day (not both meds). It takes about two months to reach noticeable improvement. Glucosamine and chondroitin for osteoarthritis ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 3. Reader submitted Q&A - Hysterectomy and chronic fatigue and fibromyalgia syndromes ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ "A lot of the members of [hysterectomy support groups] are complaining about joint pain, and FMS, either before and/or after their hysterectomy. I also noted when I was on an endo support group that there was a lot of fibromyalgia and CFS amongst the members. Is there a connection? " These two syndromes have fatigue, muscle and joint pains, headaches and other symptoms in common. They can both produce pelvic pain. Fibromyalgia syndrome is associated with menstrual abnormalities including both skipping menses as well as more frequent bleeding. There may be some hormonal abnormalities associated with these conditions such as lower adrenal cortisol or DHEA but it is not clear that it not just because they are both stressful diseases. For a discussion of these two syndromes and how they may be related to hysterectomy, see: Hysterectomy and CFS and FMS ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 4. Silicone implants unrelated to connective diseases ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ In spite of the fact that there has been massive litigation over the possibility that silicone breast implants may cause some autoimmune connective tissue diseases, the medical evidence has been lacking to prove this. This meta-analysis of 20 studies in the medical literature that have investigated this subject was recently reported in the New England Journal of Medicine. The authors found no increased risk ratios of: rheumatoid arthritis systemic lupus erythematosus scleroderma or systemic sclerosis Sjogren's syndrome in women who had silicone-gel-filled breast implants or any other type of breast implant. They concluded that "from a public health perspective, breast implants appear to have a minimal effect on the number of women in whom connective-tissue diseases develop, and the elimination of implants would not be likely to reduce the incidence of connective-tissue diseases." ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 5. Genetically altered food squabble ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ You may have already made up your mind about seeds that have been genetically altered in order to make them disease and insect resistant in crop production. People are concerned that the genetic alterations may also have the potential to cause human disease because this is an area that we are not very familiar with. Without any studies this was mainly a theoretical argument and concern but in the late fall of 1999, one study came out claiming that experimental rats fed genetically modified potatoes ended up having some cellular changes in their stomachs and intestines (we do not know that these changes are of concern but the fact that there were any demonstrable changes is of concern). For an understandable, scientific discussion of these findings, you may want to visit the "WHYFILES" at the University of Wisconsin. This is a subject that bears following. ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 6. Health tip to share - Pecans and cholesterol ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ About two ounces of pecan nuts a day lowers serum cholesterol by about 10% - FRJ Pecans lower cholesterol If you have discovered ways of coping with a disease or condition and it works for you, please share it with us: Health tip suggestion form ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 7. Humor is healthy ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ "I had the strangest dream last night," a woman was telling her psychiatrist. "I saw my mother, but when she turned around to look at me, I noticed that she had your face. And you can imagine, I found this very disturbing, and in fact I woke up immediately, and couldn't get back to sleep. I just lay there in bed waiting for morning to come, and then I got up, drank a Coke, and came right over here for my appointment. I thought you could help me explain the meaning of this strange dream." The psychiatrist was silent for a full minute before responding, "A Coke? You call that a breakfast! ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ That's it for this time. Your BACKUPMD on the Net. Rick Frederick R. Jelovsek MD ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
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